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Differential proteome of the striatum from A30P α-Synuclein transgenic mouse model of parkinson's disease
2013 Edition, May 1, 2013 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Parkinson's disease (PD) is a multifactorial, neurodegenerative disease where etiopathogenesis are not fully understood. Mutations in α-Synuclein (α-Syn) were the first genetic defect linked to PD. They are deposited in Lewy bodies (LBs) characteristic for...

Improved reproducibility in dopamine D/sub 2/-receptor studies with automatic segmentation of striatum from PET images
2004 Edition, Volume 5, January 1, 2004 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Manual region-of-interest (ROI) definition is the conventional basis for calculating regional receptor binding potential values in neuroreceptor PET studies. In this study, we propose a fully automatic method to extract the left and right caudate and putamen from 11...

Protein profiling of striatum and substantia nigra from hemiparkinsonian rat model by offgel-HPLC-MS/MS
2013 Edition, May 1, 2013 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Parkinson's disease (PD) is a common neurodegenerative disease. The prevalence of PD among people over 65 years old is about 2 % and it is induced by multifactor including age, gene and environment. Recently, proteomics are increasingly being applied to identify...

Extraction of error related local field potentials from the striatum during environmental perturbations of a robotic arm
2013 Edition, November 1, 2013 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

A time-frequency analysis based on wavelet transform was carried out to extract error related local field potentials (LFPs) resulting from undesired action perturbations during the control of a robotic effector. During this study, a marmoset monkey controlled the...

Direct Estimation of Voxel-wise Neurotransmitter Response Maps from Dynamic PET Data
Volume PP - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Computational methods, such as the linear parametric neurotransmitter PET (lp-ntPET) method, have been developed to characterise the transient changes in radiotracer kinetics in the target tissue during endogenous neurotransmitter release. In this paper, we describe and...

From habits to actions: dorsolateral striatum lesions alter the content of learning
2002 Edition, Volume 3, January 1, 2002 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Actions are controlled by the expectation of an outcome, whereas habits are elicited by the prevailing stimuli, autonomous of the outcome. In this study, the dorsolateral striatum is shown to be necessary for the formation of a habit....

The Effects of Curcumin on the Proteome of L02 Cells
2012 Edition, May 1, 2012 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Objective: To study the effects of curcumin on the proteome of L02 cells with the techniques of two-dimensional gel electrophoresis and mass-spectrometric. Methods: The total proteins of the untreated L02 cells and the L02...

Meta BCI : Hippocampus-striatum network inspired architecture towards flexible BCI
2018 Edition, January 1, 2018 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Classifying neural signals is a crucial step in the brain-computer interface (BCI). Although Deep Neural Network (DNN) has been shown to be surprisingly good at classification, DNN suffers from long training time and catastrophic forgetting. Catastrophic forgetting refers to a...

Automatic Versus Semi-Automatic method for the striatum specific uptake ratio quantification based on [123I]FP-CIT SPECT images
2019 Edition, February 1, 2019 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

The aim of this work was to implement an automatic application (AA) for the quantification of the striatum transaxial slices based on [123I]FP-CIT SPECT (Single Photon Emission Tomography) images. A sample of 68 subjects with and without pathology...

Transcriptome Study of Brain Nerve Impairment induced by Pb Exposure
Volume PP - IEEE - Institute of Electrical and Electronics Engineers, Inc.

With the introduction of the global brain science program, brain science and cognitive science are listed as one of the important research areas in China, the goal of which is to understand the function of the brain. In...

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