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Chemical imaging of μ-TAS using terahertz chemical microscope
2010 Edition, September 1, 2010 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

A terahertz chemical microscope (TCM) has been carried out to visualize the chemical potential distribution in μ-TAS. Since the TCM can detect the chemical potential at exactly where the femtosecond laser was irradiated, the spatial resolution less...

Ultrasensivite three dimensional nanoscale chemical imaging
2015 Edition, October 1, 2015 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

We demonstrate nano-scale 3-dimensional chemical imaging by extreme ultraviolet laser with 75 nm lateral, 20 nm depth resolution, and 0.01 aM sensitivity. 3D composition images of a single micro-organisms were obtained.

THz Chemical Imaging for Biological Applications
2011 Edition, Volume 1, September 1, 2011 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

THz spectroscopy is advantageous in analytical chemistry because it can detect and identify intermolecular interactions in chemical compounds, such as hydrogen bonds and hydrations, and molecular networks. Recent advances in THz components, such as ultrashort pulsed lasers and...

Automatic Recognition of Chemical Images
2007 Edition, September 1, 2007 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Images of chemical molecules can be produced, manipulated, simulated and analyzed using sophisticated chemical software. However, in the process of publishing such images into scientific literature, all their chemical significance is lost....

High-speed chemical imaging inside a microfluidic channel
2013 Edition, June 1, 2013 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. The chemical imaging system is based on the principle of the light-addressable potentiometric sensor (LAPS), which is a...

An adaptive ISFET chemical imager chip
2008 Edition, May 1, 2008 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

A CMOS based ion sensitive chemical imager chip is presented for real time spatio- temporal monitoring of chemical activity. Ion-sensitive field effect transistors (ISFETs) implemented on an unmodified process (AMS 0.35 um) are used as the chemical input to...

The interplay of chemometrics and hyperspectral chemical imaging
2011 Edition, June 1, 2011 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

While originally pioneered for use in airborne based imaging of the surface of the earth, hyperspectral imaging (HSI) has now entered the analytical chemistry laboratory and the field of online process automation [1,2]. The advent of chemometrics has...

A low-power, offset-corrected potentiostat for chemical imaging applications
2013 Edition, February 1, 2013 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

Traditional potentiostat designs often focus on high accuracy using high precision discrete components and often involve a limited number of discrete electrodes. Modern medicine and biological research require the use of high-density biosensor arrays to gain a better...

In-situ chemical imager [for planetary exploration]
2001 Edition, Volume 1, January 1, 2001 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

A variety of in-situ planetary exploration tasks such as particulate analysis or life detection require a tool with a capability for combined imaging and chemical analysis with submicron spatial resolution. In our instrument, spatially resolved chemical imaging is...

A CMOS-Based ISFET Chemical Imager With Auto-Calibration Capability
2011 Edition, Volume 11, December 1, 2011 - IEEE - Institute of Electrical and Electronics Engineers, Inc.

This paper presents a novel auto-calibration technique for eliminating sensor mismatch in CMOS-based chemical imagers. Designed using an 8 × 8 array comprising of pH-sensitive ion-sensitive field-effect transistors (ISFETs), the chemical imager is capable...

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