Tsinghua University Press Ltd. - Characterization of antibody responses against the 2F5 epitope ELDKWA using HIV-1 Env-mediated membrane fusion and neutralization assays

Author(s): Yue Cao ; Yinghua Hen
Publisher: Tsinghua University Press Ltd.
Publication Date: 1 August 2010
Volume: 15
Page(s): 447 - 451
ISSN (Electronic): 1007-0214
DOI: 10.1016/S1007-0214(10)70086-9

The epitope ELDKWA, which is located in the membrane-proximal external region (MPER) of HIV-1 gp41, is an important neutralizing epitope. The human monoclonal antibody (mAb) 2F5 against this... View More