IEEE - Institute of Electrical and Electronics Engineers, Inc. - DNA-modified siRNA-dependent gene silencing with reduced off-target effect is induced through a pathway parallel to that for siRNA-mediated RNA interference

2008 International Symposium on Micro-NanoMechatronics and Human Science

Author(s): K. Ui-Tei ; S. Zenno ; Y. Naito ; F. Takahashi ; K. Nishi ; Aya Juni ; A. Tanaka ; K. Saigo
Publisher: IEEE - Institute of Electrical and Electronics Engineers, Inc.
Publication Date: 1 November 2008
Conference Location: Nagoya, Japan
Conference Date: 6 November 2008
Page(s): 339 - 345
ISBN (CD): 978-1-4244-2919-6
ISBN (Paper): 978-1-4244-2918-9
DOI: 10.1109/MHS.2008.4752474
Regular:

RNA interference (RNAi) is mediated by 21 nucleotides of short interfering RNA (siRNA) through sequence-specific cleavage of the cognate transcript. The position-dependent function of... View More

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