The S100 family is a class of calcium-regulated proteins with EF-hand. They are widely distributed and are implicated in diverse intracellular and extracellular physiological processes. A study of the S100 family using computational biology methods such as multiple sequence alignment, structural ali...

The concept of Cooperative Work Environment (CWE) is introduced. Three key elements of CWE, inforrration integration, process integration, and organization integration, are analysed. An application framework of CWE is prcoosed and with this framework a CE CWE based on Lotus Notes/Domino and Intel Pr...

The limitations of traditional approaches to selection problems are examined. A problemsolving strategy is presented in which decision-support and knowledge-based techniques play complementary roles. An approach to the representation of knowledge to support the problem-solving strategy is presented ...

The epitope ELDKWA, which is located in the membrane-proximal external region (MPER) of HIV-1 gp41, is an important neutralizing epitope. The human monoclonal antibody (mAb) 2F5 against this epitope shows broad neutralizing activity toward many HIV strains. However, several reports have shown that t...

Efficient support for querying large-scale resource description framework (RDF) triples plays an important role in semantic web data management. This paper presents an efficient RDF query engine to evaluate SPARQL queries, where the inverted index structure is employed for indexing the RDF triples. ...