IEEE - Institute of Electrical and Electronics Engineers, Inc. - Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness

Author(s): Huaming Yan ; Monica Romero-Lopez ; Hermann B. Frieboes ; Christopher C. W. Hughes ; John S. Lowengrub
Sponsor(s): IEEE Engineering In Medicine and Biology Society
Publisher: IEEE - Institute of Electrical and Electronics Engineers, Inc.
Publication Date: 1 March 2017
Volume: 64
Page(s): 538 - 548
ISSN (Electronic): 1558-2531
ISSN (Paper): 0018-9294
DOI: 10.1109/TBME.2016.2615566
Regular:

Objective: In glioblastoma, the crosstalk between vascular endothelial cells (VECs) and glioma stem cells (GSCs) has been shown to enhance tumor growth. We propose a multiscale mathematical model... View More

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